New Polyalkynyl Dendrons and Dendrimers: Click Chemistry with Azidomethylferrocene and Specific Anion and Cation Electrochemical Sensing Properties of the 1,2,3-Triazole-Containing Dendrimers

摘要

The synthesis and use of the new tris-alkynyl dendrons 2 to 5 are reported,including the Williamson reaction of 5 with 9-iodo (9), 27-iodo (11),and 81-iodo (12) dendritic cores to yield 27-alkynyl (13), 81-alkynyl (14), and 243-alkynyl (15) dendrimers. Socalled click reactions of these three dendrimers with azidomethylferrocene (20) give 27-ferrocenyl (16), 81-ferrocenyl (17), and 243-ferrocenyl (18) dendrimers. Electrochemical recognition of oxo-anions (H2PO4 and ATP2) and Pd2+ cation has been compared using the three polyferrocenyl dendrimers. Derivatization of Pt electrodes with the dendrimers for recognition becomes more facile with increasing size of the dendrimer. This first click dendrimer bearing 243-ferrocenyl groups is the best one in the series to obtain robust, recyclable modified Pt electrodes, whereas previous click ferrocenyl dendrimers have not been suitable for this purpose.