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Association between adiposity indices and cardiometabolic risk factors among adults living in Puerto Rico.

机译:居住在波多黎各的成年人中,肥胖指数与心脏代谢危险因素之间的关联。

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Objective: To compare the general adiposity index (BMI) with abdominal obesity indices (waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR)) in order to examine the best predictor of cardiometabolic risk factors among Hispanics living in Puerto Rico. Design: Secondary analysis of measurements taken from a representative sample of adults. Logistic regression models (prevalence odds ratios (POR)), partial Pearson's correlations (controlling for age and sex) and receiver-operating characteristic (ROC) curves were calculated between indices of obesity (BMI, WC, WHR and WHtR) and blood pressure, HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), total cholesterol (TC):HDL-C, TAG, fasting blood glucose, glycosylated Hb, high-sensitivity C-reactive protein (hs-CRP), fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and an aggregated measure of cardiometabolic risk. Setting: Household study conducted between 2005 and 2007 in the San Juan Metropolitan Area in Puerto Rico. Subjects: A representative sample of 858 non-institutionalized adults. Results: All four obesity indices significantly correlated with the cardiometabolic risk factors. WHtR had the highest POR for high TC:HDL-C, blood pressure, hs-CRP, fibrinogen and PAI-1; WC had the highest POR for low HDL-C and high LDL-C and fasting blood glucose; WHR had the highest POR for overall cardiometabolic risk, TAG and glycosylated Hb. BMI had the lowest POR for most risk factors and smallest ROC curve for overall cardiometabolic risk. Conclusions: The findings of the study suggest that general adiposity and abdominal adiposity are both associated with cardiometabolic risk in this population, although WC, WHR and WHtR appear to be slightly better predictors than BMI.
机译:目的:将一般肥胖指数(BMI)与腹部肥胖指数(腰围(WC),腰臀比(WHR)和腰围身高比(WHtR))进行比较,以探讨肥胖的最佳预测指标。居住在波多黎各的西班牙裔患者中的心脏代谢危险因素。设计:从成年人的代表性样本中获得的测量结果的二次分析。在肥胖指数(BMI,WC,WHR和WHtR)和血压之间计算了Logistic回归模型(患病几率(POR)),部分皮尔逊相关性(控制年龄和性别)和接收者操作特征(ROC)曲线,高密度脂蛋白胆固醇(HDL-C),低密度脂蛋白胆固醇(LDL-C),总胆固醇(TC):HDL-C,TAG,空腹血糖,糖基化Hb,高敏感性C反应蛋白(hs-CRP),纤维蛋白原,纤溶酶原激活物抑制剂1(PAI-1)和心脏代谢风险的综合量度。地点:2005年至2007年之间在波多黎各的圣胡安市区进行的家庭研究。受试者:858名非住院成人的代表性样本。结果:所有四个肥胖指数均与心脏代谢风险因素显着相关。 WHtR对高TC:HDL-C,血压,hs-CRP,纤维蛋白原和PAI-1具有最高的POR; WC对于低HDL-C和高LDL-C和空腹血糖具有最高的POR; WHR的总体心脏代谢风险,TAG和糖基化Hb的POR最高。对于大多数危险因素,BMI的POR最低,而总体心脏代谢风险的ROC曲线最小。结论:该研究结果表明,该人群的一般肥胖和腹部肥胖都与心脏代谢风险有关,尽管WC,WHR和WHtR似乎比BMI更好。

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