首页> 外文期刊>Proceedings of the Institution of Mechanical Engineers, Part H. Journal of Engineering in Medicine >Analysis of the stent expansion in a stenosed artery using finite element method: Application to stent versus stent study
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Analysis of the stent expansion in a stenosed artery using finite element method: Application to stent versus stent study

机译:狭窄动脉中支架扩张的有限元分析:在支架与支架研究中的应用

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摘要

In this article, finite element method is used to investigate the mechanical behavior of a stent and to determine the biomechanical interaction between the stent and the artery in a stenting procedure. The main objective of this study is to reach to a model close to a real condition of coronary stent placement. Unlike most of the models proposed in the literature, all the steps of the deployment of a stent in the stenotic vessel (i.e. pressure increasing, constant load pressure and pressure decreasing) are simulated in this article to show the behavior of the stent in different stages of implantation. The results indicate that the first step of deployment, that is, pressure increasing, plays a main role in the success of stent implantation. So that, in order to compare the behavior of different types of stents, it is sufficient to compare their behavior at the end of pressure increasing step. In order to show the application of the findings in stent versus stent studies, three commercially available stents (the Palmaz-Schatz, Multi-Link and NIR stents) are modeled and their behavior is compared at the end of pressure increasing step. The effect of stent design on the restenosis rate is investigated. According to the findings, the possibility of restenosis is lower for Multi-Link and NIR stents in comparison with Palmaz-Schatz stent which is in good agreement with clinical results. Therefore, the testing methodology outlined here is proposed as a simple and economical alternative for stent versus stent complicated clinical trials.
机译:在本文中,使用有限元方法研究支架的机械性能,并确定在支架植入过程中支架与动脉之间的生物力学相互作用。这项研究的主要目的是建立一个与冠状动脉支架置入的实际情况相近的模型。与文献中提出的大多数模型不同,本文模拟了支架在狭窄血管中展开的所有步骤(即压力增加,恒定负载压力和压力减小),以显示支架在不同阶段的行为植入。结果表明,展开的第一步,即压力增加,在支架植入成功中起主要作用。因此,为了比较不同类型支架的行为,在压力增加步​​骤结束时比较它们的行为就足够了。为了显示研究结果在支架与支架研究中的应用,对三种市售支架(Palmaz-Schatz,Multi-Link和NIR支架)进行了建模,并在压力增加步​​骤结束时比较了它们的行为。研究了支架设计对再狭窄率的影响。根据研究结果,与Palmaz-Schatz支架相比,Multi-Link和NIR支架发生再狭窄的可能性更低。因此,本文概述的测试方法被建议作为支架与支架复杂临床试验的一种简单且经济的替代方案。

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