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3D chips assess drug viability

机译:3D芯片评估药物生存能力

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摘要

Scientists in Germany have developed a new 3D chip for the rapid and cheap assessment of potential anticancer drugs. Andrea Robitzki and colleagues at the University of Leipzig have made a chip for the ultrafast characterisation of both 3D tissue samples, and for screening compounds to assess their anticancer activity. 3D multicellular cultures are commonly used to mimic in vivo conditions in tumours, as single cell assays do not give sufficiently realistic responses to anticancer drugs. However, to date screening devices for these 3D cultures are not advanced enough to become commercially available.
机译:德国的科学家开发了一种新型3D芯片,用于快速,廉价地评估潜在的抗癌药物。莱比锡大学的Andrea Robitzki及其同事已制造出一种芯片,用于对两种3D组织样品进行超快速表征,并用于筛选化合物以评估其抗癌活性。 3D多细胞培养通常用于模拟肿瘤中的体内状况,因为单细胞分析不能对抗癌药物产生足够真实的反应。但是,迄今为止,用于这些3D文化的筛选设备还不够先进,无法商用。

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