Volatile Release from Liquids:A Comparison of In Vivo APCl-MS,In-mouth headspace Trapping and In vitro Mouth Model Data

摘要

In-mouth volatilej release form flavoured water was followed using atmospheric pressure chemical ionization-mass spectrometry(APCl-MS0or usigna hand-held,computer-controlled device based on sequential trapping of flavours on Tenasx traps.the present results verify recent in vitro data obtained witha sophisticated,fully computerized mouth model apparatus and confirm its validity for the simulation of in-mouth dynamic volatile release.In-nose APCl-MS measurements showed considerable person-to-person variability in non-trained individuals durign drinking due to subconscious control of muscles durign swallowing and subsequent breathing.Data showed a 'swallow breath'volume reachign the nasal cavity from the throat,not from the mouth cavity.Flavour enriched air from the mouth was shown to be transported to the nose(via exhalation)immediately after the swallowign event,but the dynamic process of volatile equilibration between reisiduals of the swallowed liquid and the exhaled air predominantly determined volatile in-nose concentration.Owing to its dynamic character,the process of volatile equilibration and release in the throat upon exhialation shouldj be similar to the in-mouth process studied in the present work.A full mechanical simulation of retronasal volatile transport,however,will remain difficult.