A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case

Hilioti Zoe; Ganopoulos Ioannis; Ajith Sabna; Bossis Ioannis; Tsaftaris Athanasios

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A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case

机译：锌指核酸酶系统在体内靶向基因组工程中的新型应用：番茄LEC1-LIKE4基因案例

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摘要

A selection-free, highly efficient targeted mutagenesis approach based on a novel ZFN monomer arrangement for genome engineering in tomato reveals plant trait modifications.

机译：基于新颖ZFN单体排列的无选择，高效靶向诱变方法，用于番茄基因组工程揭示了植物性状的修饰。

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来源
《Plant Cell Reports》 |2016年第11期|共15页
作者
Hilioti Zoe; Ganopoulos Ioannis; Ajith Sabna; Bossis Ioannis; Tsaftaris Athanasios;
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正文语种 eng
中图分类植物细胞学;
关键词
Transcription factor; Zinc finger nuclease technology; Heterochronic; Development; Tomato; Fruit;

机译：转录因子;锌指核酸酶技术;等时;发育;番茄;果;

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1. A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case [J] . Hilioti Zoe, Ganopoulos Ioannis, Ajith Sabna, Plant Cell Reports . 2016,第11期

机译：锌指核酸酶系统在体内靶向基因组工程中的新型应用：番茄LEC1-LIKE4基因案例
2. Targeted genome engineering via zinc finger nucleases [J] . Seokjoong Kim, Jin-Soo Kim Plant Biotechnology Reports . 2011,第1期

机译：通过锌指核酸酶的靶向基因组工程
3. Zinc finger nuclease-expressing baculoviral vectors mediate targeted genome integration of reprogramming factor genes to facilitate the generation of human induced pluripotent stem cells [J] . PhangR.-Z., TayF.C., GohS.-L., Stem cells translational medicine. . 2013,第12期

机译：表达锌指核酸酶的杆状病毒载体介导重编程因子基因的靶向基因组整合，以促进人类诱导的多能干细胞的产生
4. Use of Multi Threaded Asynchronous DNA Sequence Pattern Searching Tool to Identifying Zinc-Finger-Nuclease Binding Sites on the Human Genome [C] . Erodula Kris, Bach Christian, Bajwa Hassan 2011 Eighth international conference on information technology: new generations . 2011

机译：使用多线程异步DNA序列模式搜索工具来识别人类基因组上的锌指核酸酶结合位点。
5. Genome engineering using DNA-binding proteins: Zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs). [D] . Reyon, Deepak. 2011

机译：使用DNA结合蛋白的基因组工程：锌指核酸酶（ZFNs）和转录激活因子样效应子核酸酶（TALENs）。
6. Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets [O] . Anthony Conway, Matthew Mendel, Kenneth Kim, 2019

机译：锌指核酸酶mRNA的非病毒传递可实现多种治疗基因靶标的高效基因组编辑
7. Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets [O] . Anthony Conway, Matthew Mendel, Kenneth Kim, 2019

机译：锌指核糖酶mRNA的非病毒递送使多种治疗基因靶标的体内基因组进行高效

A novel arrangement of zinc finger nuclease system for in vivo targeted genome engineering: the tomato LEC1-LIKE4 gene case

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