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Medicine safety: experiences and perceptions of the general public in Liverpool.

机译:药物安全性:利物浦公众的经验和看法。

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PURPOSE: To determine whether views of medicine safety, awareness of medicines' side effects and reporting behaviours were related to experiences of suspected side effects among the general public. METHOD: Street interviews with the general public in central Liverpool, using closed and open questions. University ethics approval was obtained. RESULTS: A total of 436 people were interviewed, most (313; 71.8%) of whom obtained a medicine at least once every 3 months, 153 (37.4%) only prescribed medicines, 73 (16.7%) only over-the-counter (OTC) medicines and 87 (19.9%) both. A total of 198 (45.4%) respondents claimed to have experienced a side effect from a prescription medicine, an OTC medicine or both, and 110 (25.2%) knew someone who had experienced a side effect. Experiences of suspected adverse drug reactions (ADRs) did not appear to influence perceptions of medicine safety, with most feeling that both prescribed and OTC medicines were safe. Only 94 (21.6%) respondents identified the Medicines and Healthcare Products Regulatory Agency as being responsible for monitoring medicine safety, and only 27 (6.2%) were aware of direct patient reporting. Once informed about direct reporting, over half said that they were strongly likely to report in the future, with the main reasons (272) for reporting being an ADR which was serious, caused hospital admission or affected daily life. CONCLUSION: Public understanding of medicine safety, how safety is monitored and how to report suspected ADRs is generally limited despite ADRs being commonly experienced. If awareness of direct patient reporting can be increased, the public appear to be willing to report and to be appropriately selective in reporting.
机译:目的:确定公众对药物安全性的看法,对药物副作用的认识和举报行为是否与可疑副作用相关。方法:在利物浦市中心对公众进行街头访谈,使用封闭式和开放式问题。获得大学伦理学批准。结果:总共对436人进行了访谈,其中大多数(313; 71.8%)每3个月至少获得一次药物,其中153(37.4%)只使用处方药,73(16.7%)仅是非处方药(非处方药)和87种(19.9%)。共有198名(45.4%)的受访者声称经历过处方药,OTC药或二者兼有的副作用,而110名(25.2%)的受访者知道有副作用。可疑药物不良反应(ADR)的经历似乎并未影响对药物安全性的看法,大多数人认为处方药和非处方药都是安全的。只有94个(21.6%)的受访者将药品和保健产品监管机构确定为负责监督药品安全的机构,只有27(6.2%)的受访者知道直接进行患者报告。一旦被告知直接报告,超过一半的人说他们将来很有可能报告,主要原因(272)是因为ADR严重,导致住院或影响日常生活。结论:尽管对药品的安全性普遍有经验,但公众对药品安全性,如何监控安全性以及如何报告可疑的药品不良反应的理解通常是有限的。如果可以提高对直接患者报告的意识,那么公众似乎愿意报告,并且在报告中要有适当的选择。

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