Risk assessment for cryptosporidium: a hierarchical bayesian analysis of human dose response data

摘要

Three dose-response studies were conducted with healithy volunteers using different Cryptosporidium parvum isolates (IOWA, TAMU, TaMU, and UCP). The study data were previously analyzed 938). ID_50s were derived using two definitions of infection: one as subjects having oocysts detected in stool by direct fluorescence assay, and the other by a clinical finding of diarrhea with or without detected oocysts (Chappell et all., 1998; Okhuysen et al., 1999).