Treatment-Related Sexual Dysfunction in Male Nonprostate Pelvic Malignancies

摘要

Treatment of testicular, penile, and bladder cancer with surgery, radiation therapy, and chemotherapy may result in significant sexual morbidity. The pathophysiology of erectile dysfunction is reviewed. The incidence of posttreatment erectile dysfunction, infertility, loss of libido, retrograde ejaculation, loss of orgasm, and sexual dissatisfaction is estimated from the published literature. Morbidity resulting from different treatment options are compared and innovative approaches which hold promise for reducing sexual dysfunction in this patient population are highlighted.