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Application of Wafer-Enhanced Electrodeionization in a Continuous Fermentation Process to Produce Butyric Acid with Clostridium tyrobutyricum

机译:硅片增强电去离子在酪氨酸丁酸梭菌连续发酵生产丁酸中的应用

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Butryic acid is an organic acid which can be produced from Clostridium tyrobutyricum. This organic acid has many applications in food and perfumes as well serving as the first step in a two-step butanol production process. However, the fermentation is product inhibited as well as producing by-products of acetic acid and lactic acid. Electrodialysis and electrodeionization were explored as ways to separate butyric acid from a fermentation broth, in situ. For butyric acid system, the current resistance for ED was almost half that of EDI indicating that ED might be a better option for a pure component separation. However, in a simulated broth containing butyric, lactic, and acetic acid, the opposite trend was found to be true. These results were used to design a fermentation experiment where ED and EDI were used to separate butyric acid from an actual fermentation. It is shown that the percentage of butyric acid (compared to other organic acids) is 84%, 85%, and 92% for no separation, ED, and EDI, respectively. Further, the productivity rate is enhanced by almost 220% when comparing EDI to no separation indicating that it may make sense to use EDI for the separation of butyric acid from a Clostridium tyrobutryicum fermentation.View full textDownload full textKeywordselectrodialysis, butyric acid, Clostridium tyrobutyricum , electrodeionizationRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/01496395.2011.618170
机译:丁酸是可从酪丁酸梭菌生产的有机酸。这种有机酸在食品和香料中具有许多应用,并且是两步丁醇生产工艺的第一步。然而,发酵受到产物的抑制以及产生乙酸和乳酸的副产物。探索了电渗析和电去离子化作为从发酵液中原位分离丁酸的方法。对于丁酸体系,ED的电流电阻几乎是EDI的一半,这表明ED可能是分离纯组分的更好选择。但是,在含有丁酸,乳酸和乙酸的模拟肉汤中,发现相反的趋势是正确的。这些结果用于设计发酵实验,其中ED和EDI用于从实际发酵中分离丁酸。结果显示,对于不分离,ED和EDI,丁酸的百分比(与其他有机酸相比)分别为84%,85%和92%。此外,与未分离EDI相比,EDI的生产率提高了近220%,这表明使用EDI分离酪氨酸丁酸梭菌发酵液中的丁酸可能有意义。查看全文下载全文关键词电渗析,丁酸,酪氨酸丁酸梭菌, electroionionisationRelated var addthis_config = {ui_cobrand:“泰勒和弗朗西斯在线”,services_compact:“ citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more”,pubid:“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/01496395.2011.618170

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