Genes Commute to Factories Before They Start Work

摘要

A new study suggests that genes whose proteins work together move to the same transcription site. The more researchers learn about gene regulation, the more complicated the story gets, First there were transcription factors, proteins that bind DNA toturn genes on. Then molecular biologists figured out that each transcription factor can either stimulate or repress gene activity, depending on which specific DNA sequence it targets. Now, another layer of control is drawing increased scrutiny, says Peter Fraser, a molecular biologist at the Babraham Institute in Cambridge, U.K.