Researchers Prevent Inheritance of Faulty Mitochondria in Monkeys

摘要

Fusing two lines of research into egg cells and embryos, Shoukhrat Mitalipov and colleagues at the Oregon Health and Science University near Portland have achieved a technical feat that could lead to new methods for preventing the inheritance of mitochondrial diseases. Mitochondria, the source of energy in animal cells, are inherited exclusively from mothers and run on their own DNA (mtDNA). In recent years, scientists have linked numerous cancers and brain diseases to malfunctioning mtDNA,rnwhich may affect up to one in 6000 people.