CELL MEMBRANE ALTERATION BY WEAK ALTERNATING ELECTRIC FIELD AT LOW FREQUENCY

B. NIKOLOVA; M. GEORGIEVA; D. SAVU; I. TSONEVA

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CELL MEMBRANE ALTERATION BY WEAK ALTERNATING ELECTRIC FIELD AT LOW FREQUENCY

机译：低频弱电场改变细胞膜

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The aim is to estimate the influence of sinusoidal (ac) field in combination with the cytostatic drug gemcitabine on the therapeutic effect of malignant cells. Electrotreatment is cell line dependent. There is threshold frequency window (1Hz) that is the most suitable for drug delivery. Hematopoietic cells are more sensitive to the electrotreatment as compared with human lymphocytes from healthy donors.

机译：目的是评估正弦曲线（ac）场与抑癌药物吉西他滨联用对恶性细胞治疗效果的影响。电处理取决于细胞系。有最适合药物输送的阈值频率窗口（1Hz）。与来自健康供体的人淋巴细胞相比，造血细胞对电疗法更为敏感。

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来源
《Romanian reports in physics》 |2012年第4期|1046-1052|共7页
作者
B. NIKOLOVA; M. GEORGIEVA; D. SAVU; I. TSONEVA;
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作者单位

Institute of Biophysics and Biomedical Engineering, Bulg. Acad. Sci., Acad. G. Bonchev str., b1. 21, 1113-Sofia, Bulgaria;

Clinic of Pathology, Laboratory of Molecular Pathology, University Hospital St. Marina, 1, Hristo Smirnenski bul. 9010 Varna, Bulgaria;

'Horia Hulubei' National Institute for Physics and Nuclear Engineering, Reactorului 30, 077125, Magurele, Romania;

Institute of Biophysics and Biomedical Engineering, Bulg. Acad. Sci., Acad. G. Bonchev str., b1. 21, 1113-Sofia, Bulgaria;

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原文格式 PDF
正文语种 eng
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electrotreatment; drug delivery; gemcitabine;

机译：电处理药物输送;吉西他滨;

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专利

1. Cell membrane alteration by weak alternating electric field at low frequency [J] . B. NIKOLOVA, M. GEORGIEVA, D. SAVU, Romanian reports in physics . 2012,第4期

机译：低频弱交流电场引起的细胞膜改变
2. A model explaining synchronization of neuron bioelectric frequency under weak alternating low frequency magnetic field [J] . A. del Moral, Maria J. Azanza Journal of magnetism and magnetic materials . 2015,第mara期

机译：解释弱交替低频磁场下神经元生物电频率同步的模型
3. Influence of low-and Superlow-frequency alternating magnetic fields on ionic permeability of cell membranes [J] . Khizhenkov P. K, Dobritsa N. V, Netsvetov M. V, Доκлады Аκадемии науκ Уκраины . 2001,第4期

机译：低频和超低频交变磁场对细胞膜离子渗透性的影响
4. Influence of Weak Combined Static and Low-frequency Alternating Magnetic Fields on Tumor Growth of Ehrlich Ascites Carcinoma in Mice [C] . V. V. Novikov, G. V. Novikov, V. O. Ponomarev, Progress in electromagnetics research symposium (PIERS 2009 Moscow) . 2009

机译：静态和低频交变弱联合磁场对小鼠腹水性腹水癌肿瘤生长的影响
5. Electrolyte dependent particle aggregation by low frequency alternating electric fields. [D] . Hoggard, James D. 2008

机译：低频交变电场引起的电解质依赖性颗粒聚集。
6. Cellular and Molecular Properties of Neurons: Ih interacts with somato-dendritic structure to determine frequency response to weak alternating electric field stimulation [O] . Enrique H. S. Toloza, Ehsan Negahbani, Flavio Fröhlich -1

机译：神经元的细胞和分子特性：Ih与体树突状结构相互作用以确定对弱交变电场刺激的频率响应
7. Application of Low-Frequency Alternating Current Electric Fields Via Interdigitated Electrodes: Effects on Cellular Viability, Cytoplasmic Calcium, and Osteogenic Differentiation of Human Adipose-Derived Stem Cells [O] . McCullen, Seth D., McQuilling, John P., Grossfeld, Robert M., 2010

机译：通过指间电极施加低频交流电场：对人类脂肪干细胞的细胞存活力，细胞质钙和成骨分化的影响。
8. Low Frequencies, Motile Cells, Measurements and Models. Part I. The Effects of Low Frequency Electric Fields on Amoebae and Their Uses as Tools for Studying Cellular Structure [R] . Friend, A. W. 1972

机译：低频率，运动细胞，测量和模型。第一部分低频电场对变形虫的影响及其作为细胞结构研究工具的应用

CELL MEMBRANE ALTERATION BY WEAK ALTERNATING ELECTRIC FIELD AT LOW FREQUENCY

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