Synthesis of halohydrins from epoxides using quaternized amino functionalized cross-linked polyacrylamide as a new solid-liquid phase transfer catalyst

摘要

Poly[N-(2-aminoethyl)acrylamido]trimethyl ammonium halide resin was developed as new solid-liquid phase transfer catalyst. This quaternized polyacrylamide-catalyzed regioselective ring opening of epoxide by halides(F, Cl, Br, I), to give halohydrins in high yield under mild conditions.