Synthesis of thiocyanohydrins from epoxides using quaternized amino functionalized cross-linked polyacrylamide as a new solid-liquid phase-transfer catalyst

摘要

Poly [N-(2-aminoethyl)acrylamido] trimethyl ammonium chloride resin was developed as a new polymeric phase-transfer catalyst. This quaternized polyacrylamide catalyzed the regioselective ring opening of epoxides by thiocyanate ion to give thiocyanohydrins in high yields under mild conditions.