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PRELIMINARY INVESTIGATION OF RADIATION DOSE TO PATIENTS FROM CARDIOVASCULAR INTERVENTIONAL PROCEDURES IN TANZANIA

机译:坦桑尼亚对心血管介入程序患者的辐射剂量进行了初步调查

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摘要

Although contemporary cardiac X-ray exams are typically set so benefits outweighs the risk, the growing use and increasing complexity of the cardiovascular interventional radiological (CVIR) procedures does increase the risk of radiation-related tissue effects and stochastic effects to the individual patients and the population. In view of these radiological concerns there is a need to investigate factors that influence the doses received by the patients and enable optimisation needed. The air kerma area product (KAP), cumulative air kerma (CAK) and fluoroscopy time (FT) to patients from two major CVIR procedures: coronary angiography (CA) and percutaneous coronary interventions (PCI), were obtained from two major hospitals in Tanzania. The CAK and KAP were determined using ionisation chambers equipped in each angiographic unit. The median values of the KAP, CAK and FT for the CA procedures were 37.8 Gy cm(2), 425.5 mGy and 7.6 min, respectively, while for the PCI were 86.5 Gy cm(2), 1180.3 mGy and 19.0 min, respectively. The overall differences among individual KAP, CAK and FT values across the two hospitals investigated differed by factors of up to 33.5, 58.7 and 26.3 for the CA, while for the PCI procedures differed by factors of up to 10.9, 25.3 and 13.8, respectively. The mean values of KAP and FT for both CA and PCI were mostly higher than those reported values for Ireland, Belgium, Greece, France, China and Australia. The third quartiles of the KAP, CAK and FT for both CA and PCI were relatively above the preliminary diagnostic reference levels proposed by the IAEA, DIMOND III and SENTINEL. The observed substantial variations of mean values of technical parameters and patient doses (KAP, CAK and FT values) observed for the CA and PCI procedures inter and intra-hospitals were mainly explained by the complexity of the CVIR procedures, the nature of pathology, patient-specific characteristics, the variation in levels of skills and experiences among IC personnel, and the different procedural protocols employed among interventional cardiologists and hospitals. The observed great variations of procedural protocols and patient doses within and across the hospitals and relative higher dose than reported values from the literature call for the need to optimise radiation dose to patient from IC procedures.
机译:尽管通常会设置当代的心脏X射线检查,以使收益大于风险,但是心血管介入放射学(CVIR)程序的使用日益增加和复杂性的确增加了与辐射相关的组织效应和对个体患者及患者的随机效应的风险。人口。考虑到这些放射学问题,需要研究影响患者所接受剂量并能够进行所需优化的因素。从两个主要的CVIR程序:冠状动脉造影(CA)和经皮冠状动脉介入治疗(PCI),为患者提供的空气比释动能面积乘积(KAP),累积空气比释动能(CAK)和透视检查时间(FT)从坦桑尼亚的两家主要医院获得。使用每个血管造影单元中配备的电离室确定CAK和KAP。 CA程序的KAP,CAK和FT的中值分别为37.8 Gy cm(2),425.5 mG​​y和7.6分钟,而PCI的中值分别为86.5 Gy cm(2),1180.3 mGy和19.0分钟。在两家接受调查的医院中,CA的个体KAP,CAK和FT值之间的总体差异最大分别为33.5、58.7和26.3,而PCI程序最大分别为10.9、25.3和13.8。 CA和PCI的KAP和FT平均值大多高于爱尔兰,比利时,希腊,法国,中国和澳大利亚的报告值。 CA和PCI的KAP,CAK和FT的第三四分位数相对高于IAEA,DIMOND III和SENTINEL提出的初步诊断参考水平。院内和院内CA和PCI手术所观察到的技术参数和患者剂量(KAP,CAK和FT值)平均值的显着变化主要是由于CVIR手术的复杂性,病理性质,患者特定的特征,IC人员之间技能和经验水平的差异以及介入心脏病学家和医院之间采用的不同程序规程。在医院内和医院之间观察到的程序规程和患者剂量的巨大变化以及相对高于文献报道值的更高剂量要求从IC程序中优化对患者的放射剂量。

著录项

  • 来源
    《Radiation Protection Dosimetry》 |2018年第4期|317-332|共16页
  • 作者单位

    Queens Univ, Dept Phys, Kingston, ON K7L 5P9, Canada;

    Univ Dar Es Salaam, Dept Phys, POB 35063, Dar Es Salaam, Tanzania;

    Queens Univ, Dept Oncol, Kingston, ON K7L 5P9, Canada;

    Muhimbili Natl Hosp, Jakaya Kikwete Cardiac Inst, POB 65000, Dar Es Salaam, Tanzania;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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