CO_2 -LASER GRAFT COPOLYMERIZATION OF HEMA AND NVP ONTO ETHYLENE-PROPYLENE RUBBER (EPR) AS BIOMATERIAL-(III)

摘要

For the purpose of improved surface hydrophilicity and biocompatibility of Ethylene-Propylene rubber 2-Hydroxyethyle methacrylate (HEMA) and N-Vinylpyrrolidone (NVP) have been grafted onto the surface of this polymer using CO_2 pulsed laser at different fluence (output power J/cm~2) as excitation source. Alveolar macrophages (AMs) cultured on the surface of unmodified films showed more cell attachment with greater degree of spreading and flattening while AMs adhered onto the modified EPR appeared rounded with minimal cytoplasmic spreading and ruffling. Percentage of AMs attached to the surface of modified EPR versus graft level has also been studied.