PULSE RADIOLYSIS STUDIES OF THE INTERACTION OF HYDROXY-CINNAMIC ACID DERIVATIVES WITH OXIDIZING OH ADDUCTS OF PYRIMIDINE

摘要

The electron transfer reactions between oxidizing OH adducts of pyrimidine with hydroxy-cinnamic acid derivatives have been investigated by pulse radiolysis. The hydroxy-cinnamic acid derivatives identified as good antioxidant for reduction of oxidizing OH adducts of pyrimidine via electron transfer reactions. From buildup kinetic analysis of radical product, the rate constants for reactions of N_3~· radical with hydroxy-cinnamic acid derivatives have been determined to be (8-11) x 10~9 dm~3 mol~(-1) s~(-1), while the rate constant of electron transfer from hydroxy-cinnamic acid derivatives to oxidizing OH adducts of cytosine or thymine were obtained to be 10~9 dm~3 mol~(-1)s~(-1).