Step test in hypertension

摘要

The physiological basis of essential hypertension is a continuing rise in the systemic vascular resistance (SVR) over time, a process which does not appear to be halted by drug treatment that normalizes diastolic blood pressure (BP). Since SVR is a major determinant of BP in the absence of left ventricular (LV) systolic dysfunction, BP rises in parallel with The SVR. This can easily be demonstrated with drugs Such as phenylnephrine or cyclosporin that increase The SVR.