5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice

Virginie Da Silva Costa-Aze; Anne Quiedeville; Michel Boulouard; François Dauphin

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5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice

机译：5-HT6受体阻滞不同地影响东pol碱引起的小鼠工作记忆，识别记忆和厌恶性学习障碍

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Blockade of 5-HT6 receptors (5-HT6R) is known to improve cognitive performances in the rodent. This improvement has been hypothesized to be the result, at least in part, of a modulation of the cholinergic neurotransmission.

机译：已知5-HT6受体（5-HT6R）的阻断可提高啮齿动物的认知能力。假设这种改善至少部分是胆碱能神经传递调节的结果。

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《Psychopharmacology》 |2012年第1期|p.99-115|共17页
作者
Virginie Da Silva Costa-Aze; Anne Quiedeville; Michel Boulouard; François Dauphin;
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作者单位

Groupe Mémoire et Plasticité comportementale (GMPc), EA 4259, Université de Caen Basse Normandie, Caen, 14032, France;

Laboratoire d’hormonologie, Pôle de biologie, Centre Hospitalier Universitaire de Caen, Avenue Côte de Nacre, 14033, Caen, Cedex 9, France;

Department of Hormonology, CHU de Caen, and Medical School, Université de Caen Basse-Normandie, Caen, 14033, France;

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正文语种 eng
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关键词
SB-271046; Scopolamine; Working memory; Recognition memory; Aversive learning; Spontaneous alternation; Place recognition; Passive avoidance; Mouse;

机译：SB-271046;东pol碱;工作记忆;识别记忆;厌恶学习;自发交替;位置识别;被动回避;鼠标;

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1. 5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice [J] . DaSilvaCosta-AzeV., QuiedevilleA., BoulouardM., Psychopharmacology . 2012,第1期

机译：5-HT6受体阻滞剂差异影响东pol碱诱导的小鼠工作记忆，识别记忆和厌恶性学习障碍
2. Serotonin 5-HT6 receptor blockade reverses the age-related deficits of recognition memory and working memory in mice. [J] . Da Silva Costa Aze V, Dauphin F, Boulouard M Behavioural Brain Research: An International Journal . 2011,第1期

机译：5-羟色胺5-HT6受体阻滞逆转了小鼠中与年龄有关的识别记忆和工作记忆缺陷。
3. Selective 5-HT6 Receptor Blockade Improves Spatial Recognition Memory and Reverses Age-Related Deficits in Spatial Recognition Memory in the Mouse [J] . Virginie Da Silva Costa, Pascal Duchatelle, Michel Boulouard, Neuropsychopharmacology . 2009,第2期

机译：选择性5-HT6受体阻滞剂改善空间识别记忆并逆转小鼠空间识别记忆中与年龄有关的缺陷
4. Electrophysiological Evidence of Working Memory Updating Deficits in Children with Learning Disabilities [C] . Chunlei Liu, Ru Yao International Conference on Arts, Design and Contemporary Education . 2017

机译：学习障碍儿童工作记忆更新赤字的电生理证据
5. The central executive system of working memory and primary memory deficits in patients with probable Alzheimer's disease. [D] . Curwin, Robbie D. 2000

机译：可能患有阿尔茨海默氏病的患者的工作记忆和原发性记忆缺陷的中央执行系统。
6. Effects of ginseol k-g3, an Rg3-enriched fraction, on scopolamine-induced memory impairment and learning deficit in mice [O] . Ike dela Peña, Seo Young Yoon, Hee Jin Kim, 2018

机译：人参醇k-g3（富含Rg3的组分）对东pol碱引起的小鼠记忆障碍和学习障碍的影响
7. Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse. [O] . Da Silva Costa, Virginie, Duchatelle, Pascal, Boulouard, Michel, 2009

机译：选择性5-HT6受体阻滞剂改善了空间识别记忆并逆转了小鼠空间识别记忆中与年龄有关的缺陷。

5-HT6 receptor blockade differentially affects scopolamine-induced deficits of working memory, recognition memory and aversive learning in mice

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