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This issue contains two reviews on neurobiological and neurocognitive aspects of depression, and a commentary and paper on transcranial magnetic stimulation (TMS) as a treatment for depression. Other sets of papers examine various aspects of common mental disorders, suicide, and alcohol use and common mental disorders. In the first review, Bhagwagar & Cowen (pp. 307-313) review recent developments in the study of persistent neurobiological abnormalities in patients recovered from depression. They found a growing body of evidence to suggest such abnormalities (e.g. changes in the availability of serotonin receptor subtypes, increases in cortisol secretion), usually observed in the acute phase, persist in recovery and after medication is stopped. However, the authors note that it is still unclear which abnormalities precede onset and which are a consequence of recurrent depressive illness.
机译:本期包含有关抑郁症的神经生物学和神经认知方面的两篇评论,以及有关经颅磁刺激(TMS)来治疗抑郁症的评论和论文。其他几套论文研究了常见精神障碍,自杀,饮酒和常见精神障碍的各个方面。在第一篇综述中,Bhagwagar&Cowen(pp。307-313)综述了抑郁症康复患者持续性神经生物学异常研究的最新进展。他们发现越来越多的证据表明这种异常(例如,5-羟色胺受体亚型可用性的改变,皮质醇分泌的增加)通常在急性期观察到,并持续恢复和停止用药后。然而,作者指出,尚不清楚哪些异常是在发作之前发生的,哪些是复发性抑郁症的结果。

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