Cell adhesion is essential for processes such as cell communication, inflammation, and microbial infection. A growing body of evidence suggests that eukaryotic cells form adhesion domains-or clusters of gripping proteins-in the early stages of adhesion, but the specific steps underlying the formation of these domains remain unclear. David Alsteens et al. (pp. 20744-20749) used atomic force microscopy (AFM) to investigate adhesion domain formation and propagation in Candida albicans, a form of yeast. The authors tugged on single adhesion proteins, known as adhesins, on the yeast cell surface using AFM probes capped with adhesin-specific antibodies.
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机译：细胞粘附对于诸如细胞通讯，炎症和微生物感染等过程至关重要。越来越多的证据表明，真核细胞在黏附的早期阶段会形成黏附结构域或抓握蛋白簇，但这些结构域形成的具体步骤仍不清楚。 David Alsteens等。 （第20744-20749页）使用原子力显微镜（AFM）研究了白色念珠菌（一种酵母形式）中粘附域的形成和繁殖。作者使用覆盖有粘附素特异性抗体的AFM探针在酵母细胞表面上研究了称为粘附素的单一粘附蛋白。
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