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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii
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Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii

机译：来自约氏疟原虫生长相关毒力表型的多个遗传杂交和基因座的连锁图谱

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摘要

The rodent malaria parasite (RMP) Plasmodium yoelii is an excellent model for studying malaria biology and pathogene-sis that are often difficult to investigate using human parasites; however, genetic studies of the parasite have been hindered by lack of genome-wide resources, such as genetic maps or a completely assembled genome. Many P. yoelii strains and subspecies exhibiting a wide range of phenotypic variations are available for studying disease and/or growth phenotypes.
机译：啮齿动物疟原虫（RMP）约氏疟原虫是研究疟疾生物学和病原体病的极好模型，这些疾病通常难以使​​用人寄生虫进行研究。但是，由于缺乏全基因组资源，例如遗传图谱或完整的基因组，阻碍了对寄生虫的遗传研究。许多表现出广泛的表型变异的约氏疟原虫菌株和亚种可用于研究疾病和/或生长表型。

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    Jian Li; Sittiporn Pattaradilokrat; Feng Zhu; Hongying Jiang; Shengfa Liu; Lingxian Hong; Yong Fu; Lily Koo; Wenyue Xu; Weiqing Pan; Jane M. Carlton; Osamu Kaneko; Richard Carter; John C. Wootton; Xin-zhuan Su;

  • 作者单位

    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China Laboratory of Malaria and Vector Research;

    Laboratory of Malaria and Vector Research;

    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China;

    Laboratory of Malaria and Vector Research;

    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China;

    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China;

    Department of Pathogenic Biology, Third Military Medical University, Chongqing 400038, People's Republic of China;

    Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health,Bethesda, MD 20892;

    Department of Pathogenic Biology, Third Military Medical University, Chongqing 400038, People's Republic of China;

    Department of Pathogen Biology, Second Military Medical University, Shanghai 200433, People's Republic of China;

    Department of Medical Parasitology, Langone Medical Center, New York University, New York, NY 10010;

    Department of Protozoology, Institute of Tropical Medicine and the Global Center of Excellence Program,Nagasaki University, Nagasaki 852-8523, Japan;

    Division of Biological Sciences, Institute of Cell, Animal and Population Biology, Ashworth Laboratories,University of Edinburgh, Edinburgh EH9 31T, United Kingdom;

    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894;

    Laboratory of Malaria and Vector Research;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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  • 入库时间 2022-08-18 00:40:58

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