Genevestigator. Facilitating Web-Based Gene-Expression Analysis

摘要

Microarray data contains a wealth of information.rnWith many journals requiring this data to be depositedrnin public databases as a condition of publishing, arngood deal of information is now publicly available.rnData generated from a specific experiment could be ofrninterest to other researchers investigating very differentrnquestions and information gleaned from multiplernexperiments can be combined, increasing the surety ofrnthe results. Public microarray databases can be used torndetermine what happens to your gene(s) of interestrnduring a specific growth stage or under stress conditions.rnConversely, the databases can be mined to lookrnat genome-wide changes in gene expression. Using arndatabase is also effective in terms of time and money tornpare down large candidate gene lists before validatingrnfunction. Many tools are available for analyzing publiclyrnavailable databases. One such tool, Genevestigator,rnwas presented in our September 2004 issue in thernarticle ‘‘GENEVESTIGATOR. Arabidopsis MicroarrayrnDatabase and Analysis Toolbox’’ by Zimmermann et al.rnAs of July 2006, it had been cited 144 times accordingrnto Thompson ISI (Thompson ISIWeb of Science, http://rnwww.isinet.com).