Improved photodynamic efficacy of thiophenyl sulfonated zinc phthalocyanine loaded in lipid nano-carriers for hepatocellular carcinoma cancer cells

Fadeel Doaa Abdel; Al-Toukhy Ghada M.; Elsharif Asma M.; Al-Jameel Suhailah S.; Mohamed Hanan H.; Youssef Tamer E.

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Improved photodynamic efficacy of thiophenyl sulfonated zinc phthalocyanine loaded in lipid nano-carriers for hepatocellular carcinoma cancer cells

机译：脂质纳米载体中负载的硫代苯基磺化锌酞菁对肝细胞癌细胞的光动力功效提高

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Background: The aim of the present study was to modify the structural activity of zinc(II)phthalocyanine by combining it with thiophenyl groups then loaded in lipid nano-carriers and evaluate its parameters required for the structure-activity relationship (SAR) for photodynamic therapy (PDT) of cancer.

机译：背景：本研究的目的是通过将锌（II）酞菁与硫苯基结合，然后将其负载在脂质纳米载体中，以修饰其结构活性，并评估其用于光动力疗法的结构-活性关系（SAR）所需的参数（PDT）的癌症。

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《Photodiagnosis and Photodynamic Therapy》 |2018年第9期|25-31|共7页
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Fadeel Doaa Abdel; Al-Toukhy Ghada M.; Elsharif Asma M.; Al-Jameel Suhailah S.; Mohamed Hanan H.; Youssef Tamer E.;
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1. New Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Mediated Photodynamic Therapy Inhibits the Proliferation of Human Hepatocellular Carcinoma Bel-7402 Cells by Triggering Apoptosis and Arresting Cell Cycle [J] . Chunhui Xia, Yu Wang, Wei Chen Molecules . 2011,第2期

机译：新型亲水/亲油性四α-（4-羧基苯氧基）酞菁锌介导的光动力疗法通过触发细胞凋亡和阻滞细胞周期抑制人肝癌细胞Bel-7402的增殖。
2. New Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Mediated Photodynamic Therapy Inhibits the Proliferation of Human Hepatocellular Carcinoma Bel-7402 Cells by Triggering Apoptosis and Arresting Cell Cycle [J] . Molecules . 2011,第2期

机译：新型亲水/亲油性四α-（4-羧基苯氧基）酞菁锌介导的光动力疗法通过触发细胞凋亡和阻滞细胞周期抑制人肝癌细胞Bel-7402的增殖。
3. Photodynamic effects of Zinc(II) phthalocyanine-loaded polymeric micelles in human nasopharynx KB carcinoma cells [J] . García Vior M.C., Marino J., Roguin L.P., Photochemistry and Photobiology: An International Journal . 2013,第2期

机译：载有锌（II）酞菁的聚合物胶束对人鼻咽KB癌细胞的光动力效应
4. Photodynamic therapy with a novel zinc phthalocyanine:an innovative approach to hepatocellular carcinoma treatment [C] . Racheal O. Ogbodu, Bianca Nitzsche, Michael Höpfner International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . -1

机译：新型锌酞菁锌的光动力疗法：一种创新的肝细胞癌治疗方法
5. The anti-cancer activities of Paeoniae Radix extracts on human hepatocellular carcinoma cell-line HepG2 and multidrug resistant human hepatocellular carcinoma cell-line R-HepG2 and their action mechanisms. [D] . Li, Lok Yee Mandy. 2004

机译：e药提取物对人肝癌细胞HepG2和多药耐药人肝癌细胞R-HepG2的抗癌活性及其作用机制。
6. New Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Mediated Photodynamic Therapy Inhibits the Proliferation of Human Hepatocellular Carcinoma Bel-7402 Cells by Triggering Apoptosis and Arresting Cell Cycle [O] . Chunhui Xia, Yu Wang, Wei Chen, 2011

机译：新型亲水性/亲脂性四α-（4-羧基苯氧基）酞菁锌介导的光动力疗法通过触发细胞凋亡和阻滞细胞周期抑制人肝癌细胞Bel-7402的增殖。
7. New Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Mediated Photodynamic Therapy Inhibits the Proliferation of Human Hepatocellular Carcinoma Bel-7402 Cells by Triggering Apoptosis and Arresting Cell Cycle [O] . Tao Li, Chunhui Xia, Yu Wang, 2011

机译：新型亲水性/亲脂性四α-（4-羧基苯氧基）酞菁锌介导的光动力疗法通过触发细胞凋亡和阻滞细胞周期抑制人肝癌细胞Bel-7402的增殖。

Improved photodynamic efficacy of thiophenyl sulfonated zinc phthalocyanine loaded in lipid nano-carriers for hepatocellular carcinoma cancer cells

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