Effect of methylene blue-induced photodynamic therapy on a Streptococcus mutans biofilm model

摘要

Background: Several studies have reported the use of antimicrobial photodynamic therapy (aPDT) to control biofilm but its efficacy depends on several factors, such as biofilm model used. This study aims to examine whether exposure to diode laser combined with methylene blue affects the bacterial viability and polysaccharide content in a Streptococcus mutans cariogenic biofilm model, which simulated least-famine' episodes of exposure to sucrose that occur in the oral cavity.