首页> 外文期刊>Pharmaceutical Research >Simultaneous FTIR Spectroscopic Imaging and Visible Photography to Monitor Tablet Dissolution and Drug Release
【24h】

Simultaneous FTIR Spectroscopic Imaging and Visible Photography to Monitor Tablet Dissolution and Drug Release

机译:同时FTIR光谱成像和可见摄影可监控片剂的溶解和药物释放

获取原文
获取原文并翻译 | 示例
获取外文期刊封面目录资料

摘要

Previous studies of hydroxypropyl methylcellulose (HPMC)-based tablet during exposure to water showed a number of ‘fronts’ moving into the tablet but led to contradictory interpretations. These fronts are related to water penetration into and dissolution of the tablet, but the exact nature can not be derived from visible photographic evidence. A method to study tablet dissolution simultaneously by Fourier transform infrared-attenuated total reflection (FTIR-ATR) imaging and macro-photography can assist in providing correct interpretation of the observed fronts.
机译:先前基于羟丙基甲基纤维素(HPMC)的片剂在接触水期间的研究表明,片剂进入了许多“前沿”,但导致了相互矛盾的解释。这些方面与水渗透到片剂中和片剂的溶解有关,但是确切的性质不能从可见的照相证据中得出。一种通过傅立叶变换红外衰减全反射(FTIR-ATR)成像和微距照相技术同时研究片剂溶解的方法,可以帮助提供对观察到的前沿的正确解释。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号