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Malignant tumours of the kidney: imaging strategy

机译:肾脏恶性肿瘤:影像学策略

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摘要

Primitive malignant renal tumours comprise 6% of all childhood cancers. Wilms tumour (WT) or nephroblastoma is the most frequent type accounting for more than 90%. Imaging alone cannot differentiate between these tumours with certainty but it plays an important role in screening, diagnostic workup, assessment of therapy response, preoperative evaluation and follow-up. The outcome of WT after therapy is excellent with an overall survival around 90%. In tumours such as those where the outcome is extremely good, focus can be shifted to a risk-based stratification to maintain excellent outcome in children with low risk tumours while improving quality of life and decreasing toxicity and costs. This review will discuss the imaging issues for WT from the European perspective and briefly discuss the characteristics of other malignant renal tumours occurring in children and new imaging techniques with potential in this matter.
机译:原始恶性肾肿瘤占所有儿童期癌症的6%。 Wilms肿瘤(WT)或肾母细胞瘤是最常见的类型,占90%以上。单独的影像学不能确定地区分这些肿瘤,但在筛查,诊断检查,评估治疗反应,术前评估和随访中起着重要作用。治疗后WT的结果非常好,总生存率约为90%。在诸如结果非常好的肿瘤中,可以将重点转移到基于风险的分层上,以在低风险肿瘤的儿童中保持出色的结果,同时改善生活质量并降低毒性和成本。这篇综述将从欧洲的角度讨论WT的影像学问题,并简要讨论儿童中发生的其他恶性肾肿瘤的特征以及在这一问题上具有潜力的新影像技术。

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