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Quality of life in children with vesicoureteral reflux

机译:输尿管反流患儿的生活质量

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Vesicoureteral reflux (VUR) is commonly diagnosed in children presenting with urinary tract infections. Antibiotic prophylaxis and ureteric surgery are standard treatments for these children. Our aim was to investigate whether health-related quality of life (HRQOL) was altered in children treated for VUR. Children aged 1–5 years with grade III or higher VUR were identified through electronic records at the Stollery Children’s Hospital. Parents of these children were mailed the TNO-AZL Netherlands Organisation for Applied Scientific Research Academic Medical Centre Quality of Life (TAPQOL) questionnaire. QOL scores for this group were compared with normative controls from the instrument’s creators using the Mann–Whitney U test. Thirty-two of the 96 (33%) mailed surveys were returned. Eight children had surgery, and 19 were treated with antibiotic prophylaxis. When comparing the VUR group with the control group, we found that anxiety and social functioning scores were significantly better in patients with VUR (p < 0.01). The VUR group had worse scores in problem behavior, stomach complaints ,and communication (p < 0.01). This study reveals that children with VUR have a reasonable QOL when compared with controls. However, the diagnosis of VUR and its management does have an impact on gastrointestinal complaints, behavior, and communication, which may occur as a result of chronic medical intervention.
机译:膀胱输尿管反流(VUR)通常被诊断为患有尿路感染的儿童。抗生素预防和输尿管手术是这些儿童的标准治疗方法。我们的目的是调查接受VUR治疗的儿童的健康相关生活质量(HRQOL)是否发生改变。 Stollery儿童医院通过电子记录识别出1至5岁的VUR达到或超过III级的儿童。这些孩子的父母被邮寄了TNO-AZL荷兰应用科学研究组织学术医学中心生活质量调查表(TAPQOL)。使用Mann–Whitney U检验,将该组的QOL得分与仪器创建者的标准对照进行比较。邮寄的96份调查中有32份(占33%)被退回。 8名儿童接受了外科手术,其中19名接受了抗生素预防治疗。当将VUR组与对照组进行比较时,我们发现VUR患者的焦虑和社交功能评分明显更好(p <0.01)。 VUR组在问题行为,胃部不适和沟通方面得分较差(p <0.01)。这项研究表明,与对照组相比,患有VUR的儿童具有合理的QOL。但是,VUR的诊断及其管理确实会对胃肠道的不适,行为和沟通产生影响,这可能是由于长期医疗干预而发生的。

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