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Medications Used to Manage Supraventricular Tachycardia in the Infant A North American Survey

机译:北美用于控制室上性心动过速的药物

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Supraventricular tachycardia is the most common pediatric arrhythmia, but there is no consensus and little evidence to guide its treatment. We sent a questionnaire to pediatric cardiologists in North America to assess the current practice pattern. Of 1534 surveys mailed, 352 (23%) were returned and 295 (19%) had complete data for analysis. In the acute setting, 11 different medications were chosen. The most commonly used in the infant without preexcitation were digoxin (42%), procainamide (21%), esmolol (13%), propranolol (10%), and amiodarone (8%). In the infant with preexcitation, propranolol (34%), procainamide (23%), esmolol (17%), amiodarone (11%), and digoxin (6%) were used. In the chronic setting, 8 different medications were chosen. The most commonly used in this scenario were digoxin (52%), propranolol (33%), amiodarone (4%), and sotalol (3%). In the infant with preexcitation, propranolol (70%), amiodarone (6%), digoxin (6%), atenolol (6%), and flecainide (5%) were used. Medication choices were influenced by additional electrophysiology training and preexcitation. Digoxin was used less in the setting of preexcitation. There are no comparative trials to explain the different medication choices. Although a number of medications may be efficacious, a randomized clinical trial is needed to offer further guidance.
机译:室上性心动过速是最常见的小儿心律失常,但尚无共识,也缺乏指导其治疗的证据。我们向北美的儿科心脏病学家发送了一份调查问卷,以评估当前的实践模式。在1534份邮寄的调查中,有352份(占23%)被退回,有295份(占19%)有完整的数据需要分析。在急性情况下,选择了11种不同的药物。在没有预激的婴儿中最常用的是地高辛(42%),普鲁卡因胺(21%),艾司洛尔(13%),普萘洛尔(10%)和胺碘酮(8%)。在有预激的婴儿中,使用普萘洛尔(34%),普鲁卡因胺(23%),艾司洛尔(17%),胺碘酮(11%)和地高辛(6%)。在慢性病中,选择了8种不同的药物。在这种情况下最常用的是地高辛(52%),普萘洛尔(33%),胺碘酮(4%)和索他洛尔(3%)。在有预激的婴儿中,使用普萘洛尔(70%),胺碘酮(6%),地高辛(6%),阿替洛尔(6%)和氟卡尼特(5%)。药物的选择受到额外的电生理训练和预激的影响。地高辛在预激时使用较少。没有比较试验可以解释不同的药物选择。尽管许多药物可能是有效的,但仍需要一项随机临床试验来提供进一步的指导。

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