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首页> 外文期刊>Pediatric Cardiology >Junctional Ectopic Tachycardia After Infant Heart Surgery: Incidence and Outcomes
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Junctional Ectopic Tachycardia After Infant Heart Surgery: Incidence and Outcomes

机译:婴儿心脏手术后结节性异位心动过速:发生率和结果。

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摘要

Junctional ectopic tachycardia (JET) is an arrhythmia observed almost exclusively after open heart surgery in children. Current literature on JET has not focused on patients at the highest risk of both developing and being negatively impacted by JET. The purpose of this study was to determine the overall incidence of JET in an infant patient cohort undergoing open cardiac surgery, to identify patient- and procedure-related factors associated with developing JET, and to assess the clinical impact of JET on patient outcomes. We performed a nested case-control study from the complete cohort of patients at our institution younger than 1 year of age who underwent open heart surgery between 2005 and 2010. JET patients were compared with an age matched control group undergoing open heart surgery without JET regarding potential risk factors and outcomes. The overall incidence of JET in infants after open cardiac surgery was 14.3 %. From multivariate analyses, complete repair of tetralogy of Fallot [adjusted odds ratio (AOR) 2.0, 95 % CI 1.12–3.57] and longer aortic cross clamp times (AOR 1.02, 95 % CI 1.01–1.03) increased the risk of developing JET. Patients with JET had longer length of intubation, intensive care unit stays, and total length of hospitalization, and were more likely to require extracorporeal membrane oxygenation support (13 vs. 4.3 %). JET is a common postoperative arrhythmia in infants after open heart operations. Both anatomic substrate and surgical procedure contribute to the overall risk of developing JET. Developing JET is associated with worse clinical outcomes.
机译:结节性异位心动过速(JET)是一种仅在儿童进行心脏直视手术后才观察到的心律失常。当前关于JET的文献还没有集中于JET发生和受到负面影响的最高风险患者。这项研究的目的是确定接受心脏直视手术的婴儿患者队列中JET的总体发生率,确定与发展JET相关的与患者和手术相关的因素,并评估JET对患者预后的临床影响。我们对2005年至2010年间接受过心脏直视手术的1岁以下患者的全部队列研究进行了嵌套病例对照研究。将JET患者与接受了未进行JET的心脏直视手术的年龄匹配对照组进行了比较潜在的风险因素和结果。心脏直视手术后婴儿JET的总发生率为14.3%。从多变量分析来看,法洛四联症的完全修复[校正比值比(AOR)2.0,95%CI 1.12-3.57]和更长的主动脉交叉钳夹时间(AOR 1.02,95%CI 1.01-1.03)增加了发生JET的风险。 JET患者的插管时间更长,重症监护病房住院时间更长,住院总时间更长,并且更有可能需要体外膜氧合作用(13 vs. 4.3%)。 JET是开胸手术后婴儿常见的术后心律失常。解剖学基质和外科手术均有助于发展JET的总体风险。发展中的JET与较差的临床结果相关。

著录项

  • 来源
    《Pediatric Cardiology》 |2012年第8期|p.1362-1369|共8页
  • 作者单位

    Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

    Division of Pediatric Cardiac Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA;

    St. Jude Children’s Research Hospital, Memphis, TN, USA;

    Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

    Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

    Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

    Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

    Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Heart defects; Congenital; Tachycardia; Ectopic junctional;

    机译:心脏缺陷;先天性;心动过速;异位连接;

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