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Effectiveness evaluation of several cattle anthelmintics via the fecal egg count reduction test

机译:通过粪便卵数减少试验评估几种牛驱虫药的有效性

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Utilizing groups of cograzed, naturally infected beef-type heifers, three fecal egg count reduction tests were conducted in the later months of 2007 at the University of Arkansas. Each test was 28 days in length consisting of individual animal fecal nematode egg counts and coprocultures. Both original and generic ivermectin injectable formulations were used in two of the tests at 0.2 mg/kg BW, with FECR percentages never exceeding 90% in either test. Oral fenbendazole was evaluated at 5 and 10 mg/kg BW, with FECR%'s exceeding 90% on all occasions, but with a precipitous drop when recently treated animals were treated at the lower dose. Evaluated in one test, injectable moxidectin given at 0.2 mg/kg BW resulted in egg count reductions of 96–92% (days 7 to 28). Also evaluated in one test, albendazole delivered orally at 10 mg/kg BW was 98% and 97% effective at 17 and 28 days post-treatment. For all tests, coprocultures conducted post-treatment contained only Cooperia spp. larvae (benzimidazole use), relatively unmodified percentages of Cooperia spp. and Haemonchus spp. larvae (ivermectin use), and primarily Cooperia spp. larvae with a small percentage of Haemonchus spp. larvae (moxidectin use).
机译:在2007年下半年,利用阿肯色自然感染的牛群小母牛组成的小群,在阿肯色大学进行了三个粪便卵数减少测试。每个测试的时间为28天,包括单个动物粪便线虫卵数和共培养。两种试验中均使用原始和通用的伊维菌素注射剂,剂量为0.2 mg / kg体重,两种试验中的FECR百分比均不超过90%。口服芬苯达唑的评估为5和10 mg / kg体重,所有情况下的FECR%都超过90%,但是当最近接受治疗的动物以较低剂量治疗时,其急剧下降。在一项测试中评估,以0.2 mg / kg BW注射的莫西菌素注射液可减少96-92%的卵数(第7至28天)。在一项测试中也进行了评估,在治疗后17天和28天,口服10毫克/千克体重的阿苯达唑有效率为98%和97%。对于所有测试,进行后处理的共原代培养仅包含木瓜属。幼虫(使用苯并咪唑),木瓜属物种的相对未修饰百分比。和Haemonchus spp。幼虫(使用伊维菌素),主要是库珀属。幼虫中含有少量Haemonchus spp。幼虫(莫昔克丁使用)。

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