A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study

L. Shepstone; R. Fordham; E. Lenaghan; I. Harvey; C. Cooper; N. Gittoes; A. Heawood; T. J. Peters; T. O’Neill; D. Torgerson; R. Holland; A. Howe; T. Marshall; J. A. Kanis; E. McCloskey

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A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study

机译：筛查老年妇女预防骨折的有效性和成本效益的实用随机对照试验：SCOOP研究的原理，设计和方法

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SCOOP is a UK seven-centre, pragmatic, randomised controlled trial with 5-year follow-up, including 11,580 women aged 70 to 85 years, to assess the effectiveness and cost-effectiveness of a community-based screening programme to reduce fractures. It utilises the FRAX algorithm and DXA to assess the 10-year probability of fracture.

机译：SCOOP是一项英国的七中心，实用，随机对照试验，为期5年，包括11580名年龄在70至85岁之间的女性，旨在评估基于社区的减少骨折筛查计划的有效性和成本效益。它利用FRAX算法和DXA评估10年骨折的可能性。

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来源
《Osteoporosis International》 |2012年第10期|p.2507-2515|共9页
作者
L. Shepstone; R. Fordham; E. Lenaghan; I. Harvey; C. Cooper; N. Gittoes; A. Heawood; T. J. Peters; T. O’Neill; D. Torgerson; R. Holland; A. Howe; T. Marshall; J. A. Kanis; E. McCloskey;
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作者单位

University of East Anglia, Norwich, UK;

University of East Anglia, Norwich, UK;

University of East Anglia, Norwich, UK;

University of East Anglia, Norwich, UK;

University of Southampton, Southampton, UK;

Queen Elizabeth Hospital, Birmingham, UK;

University of Bristol, Bristol, UK;

University of Bristol, Bristol, UK;

University of Manchester, Manchester, UK;

University of York, York, UK;

University of East Anglia, Norwich, UK;

University of East Anglia, Norwich, UK;

University of East Anglia, Norwich, UK;

University of Sheffield, Sheffield, UK;

University of Sheffield, Sheffield, UK;

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正文语种 eng
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关键词
Clinical trial; Fracture prevention; Screening; United Kingdom;

机译：临床试验;骨折预防;筛查;英国;

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专利

1. A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study [J] . ShepstoneL., FordhamR., LenaghanE., Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA . 2012,第10期

机译：筛查老年妇女预防骨折的有效性和成本效益的实用随机对照试验：SCOOP研究的原理，设计和方法
2. Design of the SALT Osteoporosis Study: a randomised pragmatic trial, to study a primary care screening and treatment program for the prevention of fractures in women aged 65?years or older [J] . P. J. M. Elders, T. Merlijn, K. M. A. Swart, BMC Musculoskeletal Disorders . 2017,第1期

机译：SALT骨质疏松研究的设计：一项随机的实用试验，旨在研究预防65岁以上女性骨折的初级保健筛查和治疗计划
3. The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial - a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults [J] . Handoll?H, Brealey?S, Rangan?A, Health technology assessment: HTA . 2015,第24期

机译：ProFHER（肱骨近端骨折：通过随机评估）试验-一项实用的多中心随机对照试验，评估成人肱骨近端骨折手术与非手术治疗的临床有效性和成本效益
4. Case study of patients participating in a randomised controlled trial of upper-limb robotic rehabilitation in acute stroke services [C] . Jackson A.E., Levesley M.C., Makower S.G., Proceedings of the IEEE/RAS-EMBS International Conference on Rehabilitation Robotics . 2015

机译：参加急性卒中服务中上肢机器人康复随机对照试验的患者的案例研究
5. Sexuality and gynaecological cancer: A randomised control trial to evaluate the effectiveness of a group psychoeducational intervention in improving the sexual health of women with gynaecological cancer treated with radiotherapy [D] . Jeffries, Sherryl Anne 2003

机译：性与妇科癌症：一项随机对照试验，旨在评估团体心理教育干预措施对经放射治疗的妇科癌症妇女改善性健康的有效性
6. Design of the SALT Osteoporosis Study: a randomised pragmatic trial to study a primary care screening and treatment program for the prevention of fractures in women aged 65 years or older [O] . P. J. M. Elders, T. Merlijn, K. M. A. Swart, 2017

机译：SALT骨质疏松症研究的设计：一项随机的实用试验旨在研究预防65岁以上女性骨折的初级保健筛查和治疗计划
7. The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults [O] . Handoll, H. H. G. (Helen), Brealey, S. (Stephen), Rangan, A. (Amar), 2015

机译：ProFHER（肱骨近端骨折：通过随机评估）试验–一项务实的多中心随机对照试验，评估成人肱骨近端骨折手术与非手术治疗的临床效果和成本效益

A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study

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