Heteroannulation of nitroketene N,S-arylaminoacetals with POCl3: A novel highly regioselective synthesis of unsymmetrical 2,3-substituted quinoxalines

摘要

A novel regioselective route for the synthesis of substituted and fused 3-chloro-2-(methylthio)quinoxalines through POCl3-mediated heteroannulation of a range of alpha-nitroketene N,S-anilinoacetals has been reported.