机译:使用分支接头的酶促偶联构建高效的均质抗体-药物偶联物
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
Departments of Physiology and Developmental Biology, The University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA;
Departments of Physiology and Developmental Biology, The University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA;
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1881 East Road, Houston, TX 77054, USA;
机译:药物接头设计的调节增强均相抗体 - 药物缀合物的体内效力
机译:基于转谷氨酰胺酶的化学-酶结合方法可产生均一的抗体-药物结合物
机译:酸可裂解的硫代马来酰胺酸接头,用于均相抗体-药物偶联
机译:通过聚糖键合的均相抗体 - 药物缀合物制备
机译:基于杂种代理的基于模型,以评估固体瘤中的抗体 - 药物缀合物
机译:通用的化学-酶结合方法可产生均一且高度有效的抗体-药物结合物
机译:均相抗体 - 药物缀合物:DAR 2抗HER2通过缀合在孤立的轻链上获得,然后由MAB组装进行缀合