Ischemic lesion typing on computed tomography perfusion and computed tomography angiography in hyperacute ischemic stroke: a preliminary study

摘要

The ability to rapidly and accurately evaluate the location and extent of hyperacute brainnischemia is of major clinical importance. Herein, we aimed to develop imaging criteria tonclassify the ischemic lesion by computed tomography (CT) perfusion (CTP) and CT angiographyn(CTA) in hyperacute ischemic stroke patient. Non-contrast-enhanced CT, CTP and CTA werenperformed in patients with symptoms of hyperacute stroke lasting ,8 hours. According to thenvolume of infarct core, ischemic penumbra and vessel status, three ischemic lesion types werendefined. Twenty-six patients were included in our study. Among them, ten patients werenclassified into severe group, 15 patients were classified into mild group and one patient wasnclassified into reversible group. In acute stroke patients, the ischemic lesion typing may assist innindividualizing therapeutic decisions for patients by possibly extending the window for givingnthrombolytics beyond the current 3 hour limit. [Neurol Res 2008; 30: 337–340]