Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort

Pallud Johan; Audureau Etienne; Noel Georges; Corns Robert; Lechapt-Zalcman Emmanuele; Duntze Julien; Pavlov Vladislav; Guyotat Jacques; Hieu Phong Dam; Le Reste Pierre-Jean; Faillot Thierry; Litre Claude-Fabien; Desse Nicolas; Petit Antoine; Emery Evelyne; Voirin Jimmy; Peltier Johann; Caire Francois; Vignes Jean-Rodolphe; Barat Jean-Luc; Langlois Olivier; Dezamis Edouard; Parraga Eduardo; Zanello Marc; Nader Edmond; Lefranc Michel; Bauchet Luc; Devaux Bertrand; Menei Philippe; Metellus Philippe

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Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort

机译：卡莫司汀片植入治疗新诊断的胶质母细胞瘤的长期结果：法国多中心队列的对照倾向匹配分析

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摘要

Background. The standard of care for newly diagnosed glioblastoma is maximal safe surgical resection, followed by chemoradiation therapy. We assessed carmustine wafer implantation efficacy and safety when used in combination with standard care.

机译：背景。新诊断的胶质母细胞瘤的治疗标准是最大程度的安全手术切除，然后进行化学放疗。当与标准护理结合使用时，我们评估了卡莫司汀晶片植入的有效性和安全性。

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来源
《Neuro-Oncology》 |2015年第12期|1609-1619|共11页
作者
Pallud Johan; Audureau Etienne; Noel Georges; Corns Robert; Lechapt-Zalcman Emmanuele; Duntze Julien; Pavlov Vladislav; Guyotat Jacques; Hieu Phong Dam; Le Reste Pierre-Jean; Faillot Thierry; Litre Claude-Fabien; Desse Nicolas; Petit Antoine; Emery Evelyne; Voirin Jimmy; Peltier Johann; Caire Francois; Vignes Jean-Rodolphe; Barat Jean-Luc; Langlois Olivier; Dezamis Edouard; Parraga Eduardo; Zanello Marc; Nader Edmond; Lefranc Michel; Bauchet Luc; Devaux Bertrand; Menei Philippe; Metellus Philippe;
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作者单位

Hop St Anne, Serv Neurochirurg, 1 Rue Cabanis, F-75674 Paris 14, France|Paris Descartes Univ, Paris, France|Inst Pasteur, Dept Histopathol & Anim Models, Paris, France;

Henri Mondor Teaching Hosp, Dept Publ Hlth, Creteil, France|Univ Paris Est Creteil, Lab Invest Clin, Creteil, France;

Ctr Lutte Canc Paul Strauss, Dept Radiotherapy, Strasbourg, France|Strasbourg Univ, Radiobiol Lab, Federat Translationnal Med Strasbourg FMTS, Strasbourg, France;

Leeds Gen Infirm, Dept Neurosurg, Leeds, W Yorkshire, England;

Caen Univ Hosp, Dept Pathol, Caen, France|CNRS, UMR 6232, CERVOxy Grp, Caen, France|Univ Caen Basse Normandie, UMR 6232, CERVOxy Grp, Caen, France|CEA, UMR 6232, CERVOxy Grp, Caen, France;

Reims Univ Hosp, Maison Blanche Hosp, Dept Neurosurg, Reims, France;

Hop St Anne, Serv Neurochirurg, 1 Rue Cabanis, F-75674 Paris 14, France|Paris Descartes Univ, Paris, France;

Pierre Wertheimer Neurol & Neurosurg Hosp, Lyon Civil Hosp, Serv Neurosurg D, Lyon, France;

Univ Brest, Univ Med Ctr, Fac Med, Dept Neurosurg, Brest, France;

Univ Hosp Pontchaillou, Dept Neurosurg, Rennes, France;

Beaujon Hosp, AP HP, Dept Neurosurg, Clichy, France;

Reims Univ Hosp, Maison Blanche Hosp, Dept Neurosurg, Reims, France;

Sainte Anne Mil Teaching Hosp, Dept Neurosurg, Toulon, France;

Pasteur Hosp, Dept Neurosurg, Colmar, France|Hautepierre Hosp, Dept Neurosurg, Strasbourg, France;

Amiens Univ Hosp, Dept Neurosurg, Amiens, France;

CHU Limoges, Serv Neurochirurg, Limoges, France;

CHU Pellegrin, Serv Neurochirurg A, Bordeaux, France;

Clairval Private Hosp, Dept Neurosurg, Marseille, France;

Rouen Univ Hosp, Dept Neurosurg, Rouen, France;

Hop St Anne, Serv Neurochirurg, 1 Rue Cabanis, F-75674 Paris 14, France|Paris Descartes Univ, Paris, France;

Paris Descartes Univ, Paris, France;

Hop St Anne, Serv Neurochirurg, 1 Rue Cabanis, F-75674 Paris 14, France|Paris Descartes Univ, Paris, France;

CHU Angers, Dept Neurosurg, Angers, France;

Amiens Univ Hosp, Dept Neurosurg, Amiens, France;

Gui de Chauliac Hosp, Dept Neurosurg, Montpellier, France;

Hop St Anne, Serv Neurochirurg, 1 Rue Cabanis, F-75674 Paris 14, France|Paris Descartes Univ, Paris, France;

Clairval Private Hosp, Dept Neurosurg, Marseille, France|CHU Angers, Dept Neurosurg, Angers, France|Aix Marseille Univ, UMR911, CRO2, Marseille, France;

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原文格式 PDF
正文语种 eng
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关键词
carmustine wafers; chemoradiotherapy; glioblastoma; surgery; survival;

机译：卡莫司汀片;放化疗;胶质母细胞瘤;手术;生存;

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专利

1. A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703 (MACS study) [J] . Tomohiro Kadota, Ryuta Saito, Toshihiro Kumabe, Japanese journal of clinical oncology. . 2019,第12期

机译：多中心随机阶段III研究，用于新诊断的最大切除的胶质母细胞植入瘤比较用替替莫氏疗法的ChemoRadiOurapy，单独使用化学疗法; 日本临床肿瘤学群体学习JCOG1703（MACS研究）
2. Extent of resection and Carmustine wafer implantation safely improve survival in patients with a newly diagnosed glioblastoma: a single center experience of the current practice [J] . Alexandre Roux, Sophie Peeters, Marc Zanello, Journal of neuro-oncology. . 2017,第1期

机译：切除术和甘蔗晶片植入的程度安全地改善了新诊断的胶质母细胞瘤患者的存活：目前实践的单一中心经验
3. Implanted carmustine wafers followed by concomitant radiochemotherapy to treat newly diagnosed malignant gliomas: Prospective, observational, multicenter study on 92 cases [J] . DuntzeJ., LitréC.-F., EapC., Annals of surgical oncology . 2013,第6期

机译：植入卡莫司汀薄酥饼并进行放射化学疗法治疗新诊断的恶性神经胶质瘤：92例病例的前瞻性，观察性，多中心研究
4. Risk Factors for Newly Diagnosed Hypertensive at Non-Diabetes Participants: A Cohort Study in Central Bogor, Indonesia [C] . Eva Sulistiowati, Marice Sihombing International Symposium on Health Research;National Congress of The Indonesian Public Health Association . 2020

机译：非糖尿病参与者新诊断的高血压危险因素：印度尼西亚中部博戈的队列研究
5. Cone-Beam Computed Tomography Analysis of Peri-implant Buccal Bone in Grafted and Native Bone: 1-Year Results from a Prospective Controlled Cohort Study [D] . Chuang, Lin-Hsin. 2021

机译：锥梁计算机断层扫描分析腹膜植入骨盆骨骨和天然骨骨：一项前瞻性控制队列研究的1年结果
6. Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort [O] . Johan Pallud, Etienne Audureau, Georges Noel, 2015

机译：卡莫司汀片植入治疗新诊断的胶质母细胞瘤的长期结果：法国多中心队列的对照倾向匹配分析
7. A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703 (MACS study) [O] . Tomohiro Kadota, Ryuta Saito, Toshihiro Kumabe, 2019

机译：单独使用ChemoRomide的ChemoRomide用ChemoRadiOurapy进行新诊断的最大切除的胶质母细胞植物的多中心随机分切胶质母细胞植物的研究。日本临床肿瘤学研究JCOG1703（MACS研究）

Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort

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