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Stimulation strategies and electrode design in computational models of the electrically stimulated cochlea: An overview of existing literature

机译:电刺激耳蜗计算模型中的刺激策略和电极设计:现有文献综述

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摘要

Since the 1970s, computational modeling has been used to investigate the fundamental mechanisms of cochlear implant stimulation. Lumped parameter models and analytical models have been used to simulate cochlear potentials, as well as three-dimensional volume conduction models based on the Finite Difference, Finite Element, and Boundary Element methods. Additionally, in order to simulate neural responses, several of these cochlear models have been combined with nerve models, which were either simple activation functions or active nerve fiber models of the cochlear auditory neurons. This review paper will present an overview of the ways in which these computational models have been employed to study different stimulation strategies and electrode designs. Research into stimulation strategies has concentrated mainly on multipolar stimulation as a means of achieving current focussing and current steering, while modeling work on electrode design has been chiefly concerned with finding the optimal position and insertion depth of the electrode array. Finally, the present and future of computational modeling of the electrically stimulated cochlea is discussed.
机译:自1970年代以来,计算模型已用于研究人工耳蜗植入刺激的基本机制。集总参数模型和分析模型已用于模拟耳蜗电位,以及基于有限差分,有限元和边界元方法的三维体积传导模型。另外,为了模拟神经反应,已经将这些耳蜗模型中的几种与神经模型相结合,这些神经模型要么是简单的激活函数,要么是耳蜗听觉神经元的活动神经纤维模型。本文将概述使用这些计算模型研究不同刺激策略和电极设计的方式。刺激策略的研究主要集中在多极刺激上,以作为实现电流聚焦和电流控制的一种手段,而电极设计的建模工作则主要与寻找电极阵列的最佳位置和插入深度有关。最后,讨论了电刺激耳蜗的计算模型的当前和未来。

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