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Rapid and segmental specific dysregulation of AQP2, S256-pAQP2 and renal sodium transporters in rats with LPS-induced endotoxaemia

机译:LPS致内毒素血症大鼠中AQP2,S256-pAQP2和肾钠转运蛋白的快速和节段特异性失调

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摘要

Background. Acute renal failure (ARF) is a frequent complication of sepsis. Characteristics of ARF in sepsis are impaired urinary concentration, increased natriuresis and decreased glomerular filtration rate (GFR), in which inducible nitric oxide synthase (iNOS) has been revealed to play a role.
机译:背景。急性肾衰竭(ARF)是脓毒症的常见并发症。败血症中ARF的特征是尿液浓度降低,排尿增多和肾小球滤过率(GFR)降低,其中诱导型一氧化氮合酶(iNOS)已发挥作用。

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