Performance evaluation of a particle-enhanced turbidimetric cystatin C assay using the Abbott Aeroset analyser and assessmentn of cystatin C-based equations for estimating glomerular filtration rate in chronic kidney disease

摘要

Introduction. Measurement of glomerular filtration rate (GFR) is critical for the diagnosis and stratification of chronic kidney disease (CKD). Recent studies have shown that cystatin C is superior to creatinine for the detection of impaired GFR, and several cystatin C-based equations for estimating GFR have been developed for this clinical application. We conducted the present study to assess the applicability of cystatin C as a routine clinical laboratory index and to determine the performance of cystatin C-based equations in estimating GFR in CKD patients in China.