Over the next decade, it should be pos- sible to produce a new generation of safe, effective and inexpensive med- icines for many of the infectious diseases that afflict the poor. To achieve this, it will first be necessary to address the lack of viable commercial markets, to scale up the global capacity for research and development (R&D), and to build a more efficient and more open mechanism for the discovery of new drugs. Governments can provide the leadership necessary to align the increasingly political issue of global health with philanthropic funding, technological capability and the new opportunities stemming from scientific progress.
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