Barend Mons's first objective would be ambitious enough for most people: to meld some of the most important biomedical databases into a single information resource. But that's just the beginning. Mons, a bioinformatician at the Erasmus Medical Centre in Rotterdam, the Netherlands, also wants to apply the Wikipedia philosophy. He's inviting the whole research community to help update a vast store of interlinked data. If he and his colleagues can pull it off — and even the project's advocates are not sure they can — they could transform the databases that are central to the work of many life scientists.
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