Modulating malaria's mayhem

摘要

The malaria parasite wreaks havoc in the body, in part by activating receptors that normally detect the presence of microbes and initiate innate immune responses. By interfering with these 'Toll-like' receptors in a mouse model of cerebral malaria, the worst symptoms of the disease can be prevented, say Ricardo Gazzinelli at the University of Massachusetts Medical School in Worcester and his team.