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Cancer genomics: Collaborative research

机译:癌症基因组学:合作研究

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When robert Strausberg started his career in 1976 as a microbiologist, studying yeast as a postdoc at Southwestern Medical School, he had no idea chat one day he'd be working in cancer genomics From a field that did not exist, it has become a promising new direction for understanding and treating cancer, attracting researchers from across scientific disciplines, some of whose expertise might not have seemed immediately useful for cancer research. "I didn't think what I was doing applied to much else," says Strausberg, now executive director of collaborative sciences at Ludwig Cancer Research in New York. But it turned out his experience was more useful than he thought. An early-stage biotechnology company, Genex, hired him to apply his knowledge of yeast to develop vaccines and drugs. His studies of yeast's mitochondrial DNA and what he'd learned about the physical mapping of DNA eventually won him the head role at the Sequencing Technology Branch at the US National Center for Human Genome Research among various other jobs at the National Institutes of Health. Because genomics is basic to biology, Strausberg's increasing knowledge helps him understand various fields important to human health, from infectious disease to agriculture. "My interest in genomics has opened a lot of doors for me."
机译:罗伯特·斯特劳斯伯格(Robert Strausberg)于1976年以微生物学家的身份开始其职业生涯,并在西南医学院(Southwestern Medical School)作为一名博士后研究酵母菌时,他不知道有一天他会从事癌症基因组学研究。理解和治疗癌症的新方向,吸引了来自各个科学领域的研究人员,其中一些专业知识可能似乎并未立即对癌症研究有用。 “我认为我所做的事情并没有应用到其他方面,”现为纽约路德维希癌症研究公司合作科学执行董事的斯特劳斯伯格说。但是事实证明,他的经历比他想像的要有用。一家早期的生物技术公司Genex雇用他,将其对酵母的了解应用于开发疫苗和药物。他对酵母线粒体DNA的研究以及对DNA物理作图的了解最终使他在美国国家人类基因组研究中心测序技术处担任主角,并在国立卫生研究院担任了其他工作。因为基因组学是生物学的基础,所以Strausberg不断增长的知识帮助他了解从传染病到农业对人类健康至关重要的各个领域。 “我对基因组学的兴趣为我打开了很多门。”

著录项

  • 来源
    《Nature》 |2015年第7547期|398b1|共2页
  • 作者

    Andrea Sottoriva;

  • 作者单位

    London's Institute of Cancer Research;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-18 02:52:30

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