DNA origami circumvents drug resistance for cancer treatment

摘要

DNA origami, a process designed by Paul Rothemund in 2006, is a method of folding a single strand of viral DNA into a desired 3D structure. A new study recently published in the Journal of the American Chemical Society demonstrates how researchers from the National Center for Nanoscience and Technology (Beijing, China) have applied the technology to develop a novel drug carrier system and attack breast cancer cells using an anti­cancer drug, doxorubicin, to which the cancer cells have gained resistance.