[(Methyl)1-11C]-Acetate Metabolism in Hepatocellular Carcinoma

Nicolas Salem; Yu Kuang; David Corn; Bernadette Erokwu; Jeffrey A. Kolthammer; Haibin Tian; Chunying Wu; Fangjing Wang; Yanming Wang; Zhenghong Lee

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[(Methyl)1-11C]-Acetate Metabolism in Hepatocellular Carcinoma

机译：[（甲基）1-11 C]-乙酸在肝细胞癌中的代谢

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Studies have established the value of [(methyl)1-11C]-acetate ([11C]Act) combined with 2-deoxy-2[18F]fluoro-d-glucose (FDG) for detecting hepatocellular carcinoma (HCC) using positron emission tomography (PET). In this study, the metabolic fate of [11C]Act in HCC was characterized.

机译：研究已经确定了[（甲基）1-11 C]-乙酸盐[[11 C] Act）与2-脱氧-2 [18 F]氟-d结合的价值。 -葡萄糖（FDG）用于使用正电子发射断层扫描（PET）检测肝细胞癌（HCC）。在这项研究中，[11 C] Act在肝癌中的代谢命运得到了表征。

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来源
《Molecular Imaging and Biology》 |2011年第1期|p.140-151|共12页
作者
Nicolas Salem; Yu Kuang; David Corn; Bernadette Erokwu; Jeffrey A. Kolthammer; Haibin Tian; Chunying Wu; Fangjing Wang; Yanming Wang; Zhenghong Lee;
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作者单位

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA;

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA;

Department of Radiology, University Hospitals Case Medical Center, 11100 Euclid Ave., Bishop Building, Room S-109B, Cleveland, OH, 44106, USA;

Department of Radiology, University Hospitals Case Medical Center, 11100 Euclid Ave., Bishop Building, Room S-109B, Cleveland, OH, 44106, USA;

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA;

Department of Radiology, University Hospitals Case Medical Center, 11100 Euclid Ave., Bishop Building, Room S-109B, Cleveland, OH, 44106, USA;

Department of Radiology, University Hospitals Case Medical Center, 11100 Euclid Ave., Bishop Building, Room S-109B, Cleveland, OH, 44106, USA;

Department of Biomedical Engineering,;

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正文语种 eng
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关键词
Acetate; Hepatocellular carcinoma (HCC); Positron emission tomography (PET); Liver cancer; Tumor metabolism; Lipid; Woodchuck; Marmota monax;

机译：醋酸盐;肝细胞癌（HCC）;正电子发射断层扫描（PET）;肝癌;肿瘤代谢;脂类;土拨鼠;早獭;

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专利

1. PET imaging of hepatocellular carcinoma with 2-deoxy-2(~18F)fluoro-D-glucose,6-deoxy-6(~18F)fluoro-D-glucose, (~1-11C)-acetate and (N-methyl~-11C)-choline [J] . N. SALEM, Y. KUANG, F. WANG, The quarterly journal of nuclear medicine and molecular imaging: official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical . 2009,第2期

机译：用2-脱氧-2（〜18F）氟-D-葡萄糖，6-脱氧-6（〜18F）氟-D-葡萄糖，（〜1-11C）-乙酸盐和（N-甲基〜 -11C）-胆碱
2. PET imaging of hepatocellular carcinoma with 2-deoxy-2(~18F)fluoro-D-glucose,6-deoxy-6(~18F)fluoro-D-glucose, (~1-11C)-acetate and (N-methyl~-11C)-choline [J] . N. SALEM, Y. KUANG, F. WANG, The quarterly journal of nuclear medicine and molecular imaging: official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical . 2009,第2期

机译：用2-脱氧-2（〜18°F）氟-d-葡萄糖，6-脱氧-6（〜18°F）氟-d-葡萄糖，（〜1-11℃） - 乙酸乙酯和（N-甲基〜 -11c） - 丘陵
3. ((Methyl)1-(11)c)-acetate metabolism in hepatocellular carcinoma. [J] . Salem N, Kuang Y, Corn D, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2011,第1期

机译：（（甲基）1-（11）c）-乙酸在肝细胞癌中的代谢
4. A NEW AUTOMATIC DETECTION APPROACH FOR HEPATOCELLULAR CARCINOMA USING 11{sup left}C-ACETATE POSITRON EMISSION TOMOGRAPHY [C] . Strong Chen, Longkin Wong, Dagan Feng IEEE International Conference on Image Processing . 2003

机译：使用11 {sup左} C-醋酸纤维正电子发射断层扫描的新型肝细胞癌自动检测方法
5. Sirt1 Deficiency Upregulates Glutathione Metabolism to Prevent Hepatocellular Carcinoma Initiation in Mice [D] . Qiu, Pengxiang. 2021

机译：SIRT1缺乏上调谷胱甘肽代谢以预防小鼠肝细胞癌的起始
6. (Methyl)1-11C-Acetate Metabolism in Hepatocellular Carcinoma [O] . Nicolas Salem, Yu Kuang, David Corn, -1

机译：（甲基）1-11c - 肝细胞癌中的代谢
7. (Methyl)1-11C-Acetate Metabolism in Hepatocellular Carcinoma [O] . Nicolas Salem, Yu Kuang, David Corn, 2010

机译：（甲基）1-11c - 肝细胞癌中的代谢

[(Methyl)1-11C]-Acetate Metabolism in Hepatocellular Carcinoma

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