Mayo Genome Consortia: A Genotype-Phenotype Resource for Genome-Wide Association Studies With an Application to the Analysis of Circulating Bilirubin Levels

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  《Mayo Clinic Proceedings》 |2011年第7期|p.606-614|共9页
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  Suzette J Bielinski High Seng Chai Jyotishman Pathak Jayant A Talwalkar Paul J Limburg Rachel E Gullerud Hugues Sicotte Eric W Klee Jason L Ross Jean-Pierre A Kocher Iftikhar J Kullo John A Heit Gloria M Petersen Mariza de Andrade;

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  SUZETTE J. BIELINSKI, PHD, HIGH SENG CHAI, PHD, JYOTISHMAN PATHAK, PHD, JAYANT A. TALWALKAR, MD, PAUL J. LIMBURG, MD, RACHEL E. GULLERUD, BA, HUGUES SICOTTE, PHD, ERIC W. KLEE, PHD, JASON L. ROSS, MBA, JEAN-PIERRE A. KOCHER, PHD, IFTIKHAR J. KULLO, MD, JOHN A. HEIT, MD, GLORIA M. PETERSEN, PHD, MARIZA DE ANDRADE, PHD, AND CHRISTOPHER G. CHUTE, MD, DRPHFrom the Division of Epidemiology (SJ. B., G.M.P), Division of Biomedical Statistics and Informatics (H.S.C., J.R, R.E.G., H.S., E.W.K., J.L.R., J.-RA.K., M.d.A., C.G.C.), Division of Gastroenterology and Hepatology (J.A.T., PJ. L.), and Division of Cardiovascular Diseases and Gonda Vascular Center (I.J. K., J.A.H.), Mayo Clinic, Rochester, MN.Funding for this research was provided by the Electronic Medical Records and Genomics (eMERGE) Network of the National Human Genome Research Institute (HG05499), Mayo Clinic Genome-wide Association Study of Venous Thromboembolism (HG04735) from the National Human Genome Research Institute (NHGRI, Gene Environment Association Studies [GENEVA] consortium), Mayo Clinic Specialized Programs of Research Excellence (SPORE) in Pancreatic Cancer (P50CA102701) from the National Cancer Institute, and Mayo Clinic Cancer Center (Genetic Epidemiology and Risk Assessment [GERA] Program). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Dr Limburg served as a consultant for Genomic Health, Ine from August 12, 2008, through April 19, 2010. Mayo Clinic has licensed Dr Urnburg's ?ntellectuai property to Exact Sciences, and he and Mayo Clinic have contractual rights to receive royalties through this agreement.An earlier version of this article appeared Online First.Individual reprints of this article are not available. Address correspondence to Suzette J. Bielinski, PhD, Division of Epidemiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 (bielinski.suzette@mayo.edu).© 2011 Mayo Foundation for Medical Education and Research,;

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