Why a Comprehensive Physical Characterization Effort of Microdialysis Membranes is Imperative for Computational Mass Transfer Studies?

摘要

Microdialysis, being a well-established sampling technique, still suffers from mass transfer limitations. Arguably, the biggest contributor to mass transfer limitation in this case is the membrane layer. To reduce limitations to mass transfer, and at the same time, increasing the performance of microdialysis probes, a concise mass transfer analysis must be done. For microdialysis probes, being relatively small in size and operating under possibly stringent biological conditions, an experimental route of analysis is less preferred compared to a computational route. This paper looks at the needs of computational mass transfer studies, and provides an idea why a comprehensive physical characterization effort is imperative for computational mass transfer studies.