Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson’s disease discerned with μSPECT and quantitative MRI

Nadja Van Camp; Ruth Vreys; Koen Van Laere; Erwin Lauwers; Dirk Beque; Marleen Verhoye; Cindy Casteels; Alfons Verbruggen; Zeger Debyser; Luc Mortelmans

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Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson’s disease discerned with μSPECT and quantitative MRI

机译：用μSPECT和定量MRI识别帕金森氏病单侧6-羟基多巴胺损伤大鼠模型的形态和功能变化

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Object In the present study, we aimed to evaluate the impact of neurodegeneration of the nigrostriatal tract in a rodent model of Parkinson’s disease on the different MR contrasts (T₂, T₁, CBF and CBV) measured in the striatum.

机译：目的在本研究中，我们旨在评估帕金森氏病啮齿动物模型中黑质纹状体神经变性对不同MR对比（T _{2 ，T _{1 ，CBF和CBV）在纹状体中测量。}}

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《Magnetic Resonance Materials in Physics, Biology and Medicine 》 |2010年第2期| p.65-75| 共11页
作者
Nadja Van Camp; Ruth Vreys; Koen Van Laere; Erwin Lauwers; Dirk Beque; Marleen Verhoye; Cindy Casteels; Alfons Verbruggen; Zeger Debyser; Luc Mortelmans;
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正文语种 eng
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关键词
Parkinson’s disease; Rat; Neurodegeneration; SPECT; MRI;

机译：帕金森氏病;大鼠;神经变性;SPECT;核磁共振;

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1. Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson's disease discerned with μsPECT and quantitative MRI [J] . Van Camp N., Vreys R., Van Laere K., Magma: Magnetic resonance materials in physics, biology, and medicine . 2010 ,第2期

机译：μsPECT和定量MRI识别帕金森氏病单侧6-羟基多巴胺损伤大鼠模型的形态和功能变化
2. Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: A longitudinal in-vivo study [J] . Molinet-Dronda Francisco, Gago Belen, Quiroga-Varela Ana, Neurobiology of disease . 2015 ,第Null期

机译：帕金森病单侧和双侧6-羟基多巴胺病变大鼠模型中单胺能PET成像及其组织病理学相关性：一项纵向体内研究
3. Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: A longitudinal in-vivo study [J] . Molinet-Dronda Francisco, Gago Belen, Quiroga-Varela Ana, Neurobiology of disease . 2015 ,第Null期

机译：单侧和双侧6-羟基多戊多胺损伤大鼠帕金森病的单侧和双侧6-羟基多胺的组织病理学相关性：纵向体内研究
4. A Brain MRI/SPECT Registration System Using an Adaptive Similarity Metric: Application on the Evaluation of Parkinson's Disease [C] . Jiann-Der Lee, Chung-Hsien Huang, Cheng-Wei Chen, Computer Vision/Computer Graphics Collaboration Techniques; Lecture Notes in Computer Science; 4418 . 2007

机译：自适应相似度量的脑MRI / SPECT配准系统：在帕金森氏病评估中的应用
5. Effects of a unilateral intrastriatal 6-hydroxydopamine model of early Parkinson's disease on midbrain dopamine neurons in rats: A stereological study [D] . Healy-Stoffel, Michelle R. 2013

机译：帕金森早期6-羟基二甲胺模型对大鼠中脑多巴胺神经元的单侧脑内血红蛋白模型的影响：立体学研究
6. Impaired Voluntary Wheel Running Behavior in the Unilateral 6-Hydroxydopamine Rat Model of Parkinsons Disease [O] . Qi Pan, Wangming Zhang, Jinyan Wang, 2015

机译：帕金森氏病单侧6-羟基多巴胺大鼠模型中的自愿性车轮跑动行为受损
7. Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson's disease discerned with microSPECT and quantitative MRI [O] . Van Camp Nadja, Vreys Ruth, Van Laere Koen, 2010

机译：用microSPECT和定量MRI识别帕金森氏病单侧6-羟基多巴胺损伤大鼠模型的形态和功能变化
8. SPECT and fMRI Analysis of Motor and Cognitive Indices of Early Parkinson's Disease: The Relationship of Striatal Dopamine and Cortical Function. [R] . Gabrieli, J. D., Stebbins, G. T. 2005

机译：早期帕金森病运动和认知指标的spECT和fmRI分析：纹状体多巴胺与皮质功能的关系。

Morphologic and functional changes in the unilateral 6-hydroxydopamine lesion rat model for Parkinson’s disease discerned with μSPECT and quantitative MRI

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