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外文期刊>Journal of Tropical Pediatrics
>Saline Nebulization before Gastric Lavage in the Diagnosis of Pulmonary Tuberculosis in Children and Adolescents
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Saline Nebulization before Gastric Lavage in the Diagnosis of Pulmonary Tuberculosis in Children and Adolescents
The main objective is to assess whether nebulization before gastric lavage (GL) improves its sensitivity for the diagnosis of childhood tuberculosis (TB). Children and adolescents suspected of pulmonary TB were randomly assigned (1 : 2) to nebulization with hypertonic saline 30 min before GL (Neb group; n = 36) or GL without prior nebulization (controls; n = 68). The proportion of positive GL smears was greater in Neb group than in the control group; however, no statistical significance was observed (36.3% vs. 22.2%; p = 0.4). Inhalation of nebulized hypertonic saline before GL did not improve TB diagnosis in this study. Nevertheless, the validation of our data will require large longitudinal studies.
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机译:主要目的是评估洗胃前的雾化(GL)是否提高其对儿童结核病(TB)诊断的敏感性。在GL前(Neb组; n = 36)或GL之前没有雾化(对照组; n = 68)之前30分钟,将疑似肺结核的儿童和青少年随机分配(1:2)接受高渗盐水雾化。 Neb组的GL阳性涂片所占比例大于对照组。但是,没有观察到统计学意义(36.3%vs. 22.2%; p = 0.4)。在本研究中吸入雾化的高渗盐水不能改善结核病的诊断。然而,我们数据的验证将需要进行大量的纵向研究。
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